Molnupiravir latest news - A new tablet for Covid-19 || molnupiravir price || molnupiravir side effects || molnupiravir availability & More | Pat fitness

  Molnupiravir - A new tablet for Covid-19

The world could soon be armed with another tool to fight the coronavirus pandemic: a twice-daily pill that has been shown to reduce the risk of hospitalization and death among people infected with the coronavirus

The drug, molnupiravir, offers another tool alongside vaccines for countries to manage the coronavirus pandemic. Here’s what you need to know about it:

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We shall discuss below points in this article.

• What is molnupiravir?
• When will molnupiravir become available?
• How is molnupiravir different from other covid-19 drugs?
• Where will molnupiravir be used?
• What is molnupiravir?

What is molnupiravir?

Molnupiravir is an antiviral pill by pharmaceutical giant Merck that aims to prevent mild to moderate cases of covid-19 from becoming severe cases that result in hospitalization or death. People who have covid-19 take the drug twice a day for five days, starting within five days of the onset of symptoms.

It was shown in an international clinical trial of 775 high-risk, unvaccinated people to cut the risk of hospitalization and death in half (the participants had at least one risk factor for severe covid-19, such as obesity or advanced age). The treatment was also shown in a separate trial to accelerate the clearance of infectious virus from the nose and throat, indicating that it may also help reduce the spread of the virus.

Still, medical experts warn that vaccines remain the primary tool against the coronavirus, as it is better to prevent people from getting the virus than to treat it after infection.

When will molnupiravir become available?

Merck has submitted data to the Food and Drug Administration following the success of its trial — which was ended early because of its positive results — seeking emergency use authorization for molnupiravir.

Merck and its partner Ridgeback Biotherapeutics said in a news release that, in addition to submitting their FDA application, they plan to apply for emergency use or marketing authorization in other countries “in the coming months.” Ahead of a decision by U.S. regulators, the companies have already started producing the pill, and have agreed to sell courses of the treatment to the United States and other countries if they get the green light.

n FDA advisory committee will meet Nov. 30 to discuss the emergency use authorization request, setting a timeline that could have the drug available by the end of the year.

How is molnupiravir different from other covid-19 drugs?

Molnupiravir stands out from other covid-19 treatments for its ease of use. The use of monoclonal antibodies, a treatment that is infused or injected, did not take off widely in the United States, as medical experts say that the treatment is costly and difficult to deliver.

Remdesivir, which, like molnupiravir is an antiviral drug, is administered by injection. It has been shown to shorten hospital stays, but for much of the past year it had unclear results on other aspects of covid-19 infection, such as severe illness or death. Gilead, the maker of remdesivir, said last month that it reduces risk of hospitalization.

A drug that can treat covid-19 could be a more palatable option for those seeking treatment and turning to unproven coronavirus cures. Ivermectin, a deworming drug commonly used in livestock and sometimes in humans, gained traction among some as a covid-19 treatment after misinformation about it spread online, prompting the FDA to warn people not to use it to treat covid-19.

Hydroxychloroquine, an anti-malaria drug President Donald Trump touted in the spring of 2020, won an emergency authorization from the FDA that proved to be premature. Clinical trials showed it did not work, and the FDA withdrew the authorization in June.

Where will molnupiravir be used?

The United States, with millions of people still unvaccinated, has made an advance purchase of $1.2 billion worth of molnupiravir — about 1.7 million treatments. Australia, Singapore and South Korea have also made purchase agreements.

The simple process to deliver, store and administer the drug could prove particularly useful in poorer nations. Vaccine distribution efforts in countries that lacked a robust medical infrastructure struggled to get shots in arms, even if they had an adequate supply, as the vaccine doses require extremely cold refrigeration and people trained to administer the shots.

Merck licensed the drug to five generic drugmakers in India to accelerate its availability in low- and middle-income countries.

Still, some experts and public health organizations have raised concerns that without a clearly articulated plan to supply countries or to negotiate contracts, global efforts to secure the drug for poorer countries could run into the same challenges Covax, the World Health Organization-backed initiative to distribute vaccine doses equitably, ran into in distributing vaccines.

“Anticipatory and preparatory work is needed to ensure rapid availability and uptake of any new treatments,” an independent report commissioned by the WHO urged, noting that the United States’ advance purchases of molnupiravir presented an example of that risk.

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